Medical droid (about Padmé): Medically, she's completely healthy. For reasons we can't explain, we are losing her.
Obi-Wan Kenobi: She's dying?
Medical droid: We don't know why. She has lost the will to live.
These words were the inevitable build up to Padme Amidala’s expected death in Star Wars Episode III: Revenge Of The Sith. No other explanation was given in the film for her death. Over the years there has been much speculation as to whether it was as simple as that or if there was something else at play?
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Theory: How Did Padme Really Die?